Cannabinoid receptors are a crucial part of the endocannabinoid system, located throughout the body and they control a variety of physiological functions and processes like mood, sensations to pain, appetite, and memory. There are two subtypes of cannabinoid receptors and they are commonly known as the CB1 and CB2 receptors.
All cannabinoid receptors in the human body are activated by plant cannabinoids, of which CBD and THC are the major actors. Although cannabinoid receptions are present in both males and females, the mechanism of action differs from men to women. Men are known to have more CB1 receptors, making them more sensitive to the hyperphagic and hypophagic effects of the CB1 receptor. The CB1 receptor is majorly expressed in the brain,liver, kidneys, and lungs and is majorly activated by THC. Men also heal faster from Traumatic Brain Injuries (TBI) due to the higher numbers of CB1 receptors in their brains.